Profiling Stem Cells in Triple Negative Breast Cancer - A PCR-Array-Based Study
نویسندگان
چکیده
منابع مشابه
Genomic profiling in triple-negative breast cancer.
Triple-negative breast cancer (TNBC) is defined by a lack of hormone receptor expression as well as lack of overexpression/amplification of HER2/neu. Patients with TNBC show a significantly worse prognosis compared to patients with other breast cancer subtypes. TNBC, however, is a heterogeneous entity both with regard to clinical/pathological characteristics and molecular biology. This review s...
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Background: Triple-negative breast cancer (TNBC) is treated with highly aggressive non-targeted chemotherapies. Safer and more effective therapeutic approaches than those currently in use are needed. Natural pomegranate peel extract (PPE) has recently been found to inhibit breast cancer progression; however, its mechanisms of action remain unclear. We hypothesized that transcriptional chan...
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Breast cancer is the most prevalent cancer in women. Although the survival rate of breast cancer has improved steadily in the past two decades, over 40,000 women die from breast cancer related complications each year. The heterogeneity of breast cancer makes the treatment of different subtypes difficult (Gonzalez-Angulo et al., 2007; Perez et al., 2010). Triple negative breast cancer (TNBC) is ...
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© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if c...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2013
ISSN: 0923-7534
DOI: 10.1093/annonc/mdt082.6